Trends of Chitosan Based Delivery Systems in Neuroregeneration and Functional Recovery in Spinal Cord Injuries

Spinal cord injury (SCI) is one of the most complicated nervous system injuries with challenging treatment and recovery. Regenerative biomaterials such as chitosan are being reported for their wide use in filling cavities, deliver curative drugs, also provide adsorption sites transplanted stem cells. Biomaterial scaffolds utilizing have shown certain therapeutic effects on spinal repair some limitations. Chitosan-based delivery cell transplantation another strategy that has decent success. Stem cells can be directed to differentiate into neurons or glia vitro. cell-based therapy, biopolymer strategies, scaffold-based strategies been advancing a combinatorial approach repair. In this review, we summarize recent progress SCI due bioactivity chitosan-based drug systems. An emphasis role neural regeneration highlighted.